http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3138924-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbb32755ecbda278fd15cfcfd3d6f1d7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B69-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0053 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3d2d9b4247273f03cbdf93044a765dd |
| publicationDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3138924-A1 |
| titleOfInvention | Application of ruthenium complexes as nucleic acid vectors of target cell nucleuses |
| abstract | The present invention discloses an application of ruthenium complexes as nucleic acid vectors of target cell nucleuses. Experimental data shows that ruthenium (II) complexes may be effectively combined with nucleic acid sequence and may effectively change morphologies of long sequence nucleic acids to make the nucleic acids be effectively delivered into viable cells via transmembrane transport and be well located within cell nucleuses, thus greatly improving transport efficiency of the nucleic acids. Based on this property, nucleic acid sequences can be conveniently transported into cells for gene therapy or fluorescent tracking or the like. The method for preparing a ruthenium coordination complex-nucleic acid complex in accordance with the present invention may provide a stable ruthenium coordination complex-nucleic acid complex in a more efficient manner and may provide many better effects. |
| priorityDate | 2015-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.