http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3137910-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f2486be400acaf00dc99dfc54630945 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-285 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2015-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66e0232fcb559ddc0dc8e51cfd4a660d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f5e270bf1064300b62b07edf9434290 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1cb6cd8b899f88f505c3527ffcaf4a5 |
| publicationDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3137910-A1 |
| titleOfInvention | Diagnosis of multiple sclerosis |
| abstract | The present invention relates to a method for diagnosing multiple sclerosis (MS) and/or clinically isolated syndrome (CIS) and/or radiologically isolated syndrome (RIS) or a predisposition for either condition in a subject, the method comprising determining the presence of an anti-KIR4.1 antibody in a sample obtained from said subject by (a) contacting said sample with a protein; and (b) detecting the formation of a protein-anti-KIR4.1 antibody complex; wherein said protein is KIR4.1, wherein glycosylation of the large extracellular domain of said KIR4.1 is as in human oligodendrocytes or glycosylation of the large extracellular domain is absent; and wherein the formation of said complex is indicative of MS, CIS, RIS or a predisposition therefor. Furthermore provided is an antibody or fragment or derivative thereof competing with the anti-KIR4.1 antibody in a sample obtained from a patient having MS. |
| priorityDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.