Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2c22d8354f2b9e583e8c47ebb4d925f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab5a78161702097f97524ce6e5cdcd7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
filingDate |
2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f1b79b24f8d9d7f1bfc778a0876a4c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4464cc7d8c2dd188433ebcd3e9a068e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92be205dc8e6dd260ccd9ac4b6f9ad39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6bd7b293c34b440a1cdf679af92b1d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68e5b16d4137abadcadb245b6f9e9e44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5092263b32e7f05ae596b73660b06739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca55540f88bea14c9d6992a081217e22 |
publicationDate |
2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3126489-A2 |
titleOfInvention |
Physical self-organizing hydrogel system for biotechnological applications |
abstract |
The invention relates to a physical self-organizing hydrogel system for biotechnological applications composed of a non-covalent network on the basis of a protein-ligand interaction, comprising a tetrameric protein as a protein and biotin or one of the derivatives thereof as a ligand, wherein biotin or one of the derivatives thereof is covalently conjugated to an end of a polymer chain of a linear or multi-arm synthetic polymer or of a single- or double-strand oligonucleotide and wherein the solid content in relation to the entire hydrogel is at least 3% and the conjugates are cross-linked by the tetrameric protein. In the hydrogel system, there is a mixture ratio as a molar equivalent ratio between the protein and the number of terminal biotinylated ends of the polymer chains in the biotin-polymer conjugate of 1:2 to 1:8. The hydrogel formation occurs with controlled kinetics on the basis of a protein-ligand interaction. |
priorityDate |
2014-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |