| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8adaddc602ad7cb7f9e2d550681bb36d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0644
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-1827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0867 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L7-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
| filingDate |
2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e52e33bc894ffb0b2112daedf46824c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ba5497436d57588cd5d5e48d3299e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4cec35c80762b42f9619d1aeb3ab28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b1d75b5d64df01c0fb82b71ecba29d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f08c7713e98d4f5403f368d65061db9 |
| publicationDate |
2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3116651-A1 |
| titleOfInvention |
Disposable, integrated microfluidic cartridge and methods of making and using same |
| abstract |
The disclosed embodiments concern microfluidic cartridges for detecting biological reactions. In some embodiments, the microfluidic cartridges are configured to perform sequencing operations on a nucleic acid sample. In one aspect, a microfluidic cartridge includes a stack of fluidics layers defining channels and valves for processing the nucleic acid sample to be sequenced, and a solid state CMOS biosensor integrated in the stack. The biosensor has an active area configured to detect signals of biological reactions, wherein substantially all of the active area is available for reagent delivery and illumination during operation. In another aspect, a microfluidic cartridge includes: (a) a flow cell including a reaction site area encompassing one or more reaction sites; (b) fluidics channels for delivering reactants to and/or removing reactants from the reaction site area; (c) a biosensor having an active area configured to detect signals of biological reactions in the reaction site area. The reaction site area is proximal to the active area of the biosensor and the reaction site area spans substantially all of the active area of the biosensor. In some embodiments, the fluidics channels do not substantially overlap with the active area of the biosensor. Methods for manufacturing and operating the microfluidic cartridges are also disclosed. |
| priorityDate |
2014-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |