Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7e87f29e0db9416800cab4f60f6c468 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
filingDate |
2015-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02943e1e7b12a5470099611546249e49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0024d64528c8692972583c50df786b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a68d71b819a5a35fa8604e1ec66dabb9 |
publicationDate |
2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3103453-A1 |
titleOfInvention |
Medicinal composition comprising diamino heterocyclic carboxamide compound as active ingredient |
abstract |
[Problem] To provide: a medicinal composition for treating an AXL-related cancer; in another embodiment, a medicinal composition for treating a cancer with high expression of AXL; and, in still another embodiment, a medicinal composition for treating a cancer that has acquired resistance through activation of AXL against anticancer agent therapy. [Solution] As the results of an examination on compounds having AXL inhibitory effect, the present inventors confirmed that specific diamino heterocyclic carboxamide compounds have AXL inhibitory effect and medicinal compositions comprising such a compound as an active ingredient have therapeutic effect on an AXL-related cancer, on a cancer with high expression of AXL in another embodiment, and on a cancer that has acquired resistance through activation of AXL against anticancer agent therapy in still another embodiment, thereby completing the present invention. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10744134-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3372231-A4 |
priorityDate |
2014-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |