http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3094749-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ebcc96a1c2a0286b77b03d7c37cbb05 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F7-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2015-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_598c3d6d5864e050ef47fd7c516b84d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2072446da2b867f644250f1cc00f62f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_024825cb30c501c8ab81c8616a14a023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65e09841ecbab4f7a356f41f542ad2b8 |
publicationDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3094749-A1 |
titleOfInvention | A method of identifying a neonate at risk of having or developing hypoxic-ischaemic encephalopathy (hie) |
abstract | A method for screening a distressed neonate for risk of having or developing HIE comprises the steps of assaying a biological sample obtained from the distressed neonate, the mother of the neonate, or from the umbilical cord or placenta, for an abundance of miR-374a in the sample, and comparing the abundance of miR-374a in the sample with a reference abundance of miR-374a, wherein a reduced abundance of miR-374a in the sample compared with the reference abundance of miR-374a is indicative of the distressed neonate being at risk of having or developing HIE. Risk of severe HIE can be determined by assaying a biological sample from the distressed neonate identified as being at risk of HIE for an abundance of a plurality of metabolites including succinate, glycerol, acetone and 3-hydroxybutyrate, providing the sum of glycerol and succinate abundance and the sum of acetone and 3-hydroxybutyrate; and correlating the sums with risk of severe HIE. |
priorityDate | 2014-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.