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publicationDate 2016-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3091031-A1
titleOfInvention Combination of a bispecific antibody with an immune modulating molecule for the treatment of a tumor
abstract Described is a combination of (i) a multifunctional antibody having specificity for an antigen present on a tumor cell and having specificity for an antigen present on a natural killer (NK) cell and (ii) at least one agent modulating an immune checkpoint molecule for the treatment of a tumor. The antibody may be a bispecific CD30/CD16 antibody and the agent can be anti-CTLA-4, anti-PD1 and ant-CD 137.
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