abstract |
A controlled release dosage form containing monomcthyl fumarate, a compound that can be metabolized into monomcthyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof, wherein the monomcthyl fumarate, a compound that can be metabolized into monomcthyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof is delivered to the subject. Also provided is a method of treating a disease or disorder (e.g., multiple sclerosis) by orally administering a controlled release dosage form containing monomcthyl fumarate, a compound that can be metabolized into monomcthyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof, wherein the monomcthyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof. |