http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3071234-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec0024795f45a646ef64b3664ab8a26d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2014-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb79d894d1d5bba6b3072981cbfa5a8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_616aa65aa5c0adedc1265d806abe1119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0faebc4f53abb14f401bbd320e45c5de |
| publicationDate | 2016-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3071234-A1 |
| titleOfInvention | Translation inhibitors in high-dose chemo- and/or high-dose radiotherapy |
| abstract | The present invention relates to an inhibitor of protein translation for use in high-dose chemotherapy and/or high-dose radiotherapy of disease; to an inhibitor of protein translation for use in a combination therapy comprising high-dose chemotherapy and/or high-dose radiotherapy of disease; and to an inhibitor of protein translation for use in preventing adverse effects of high-dose chemotherapy and/or high-dose radiotherapy or for preventing radiation syndrome in a subject. Moreover, the present invention relates to a combined preparation for simultaneous, separate or sequential use comprising at least one inhibitor of protein translation or a pharmaceutically acceptable salt thereof; and at least one chemotherapeutic agent for use in high- dose chemotherapy of disease; to the use of an inhibitor of protein translation in high-dose chemotherapy and/or high-dose radiotherapy of disease; and to a medicament for the therapy of disease which contains (i) at least one inhibitor of protein translation or a pharmaceutically acceptable salt thereof, (ii) at least one chemotherapeutic agent, and (iii) at least one pharmaceutically acceptable carrier. Further, the present invention relates to a kit comprising at least one inhibitor of protein translation and instructions on administering high-dose chemotherapy and/or instructions on administering high-dose radiotherapy in the presence of said inhibitor of protein translation; as well as to improved methods of preventing in a subject requiring high-dose chemotherapy and/or high-dose radiotherapy adverse events caused by said therapy or therapies, of improving a medical condition requiring high-dose chemotherapy and/or high-dose radiotherapy; and of treating a subject in need of high-dose chemotherapy and/or high-dose radiotherapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114656435-A |
| priorityDate | 2013-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 385.