http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3061820-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06c283f18126fcae60d7dd3a66d06f38 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2015-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7be038af2c14f1c803cab3c9fafa84d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8ed00d3acfe2556a1f9bec436621561 |
| publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3061820-A1 |
| titleOfInvention | Rapid depletion and reversible accumulation of proteins in vivo |
| abstract | The present invention relates to a process for producing a temperature-sensitive conditionally mutant multicellular organism using a low-temperature N-terminal degradation cassette or a vector comprising it to transfect or transform at least one cell or part of a multicellular organism, thereby obtaining the temperature-sensitive conditional mutant of the multicellular organism or part thereof. Further, the present invention relates to a low-temperature N-terminal degradation cassette comprising nucleotide sequences encoding at least a temperature-sensitive DHFR protein, a destabilizing amino acid, a ubiquitin moiety, as well as a protein of interest. |
| priorityDate | 2015-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 292.