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filingDate 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77707d6cce593c4de052fe4a8619dab8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a846097c4621226db2369c4d5031a873
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publicationDate 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3060254-A1
titleOfInvention Radioluminescent compound for radiotherapy and deep photodynamic therapy and device for deep photodynamic therapy
abstract The present invention relates to a radioluminescent compound for radiotherapy and deep photodynamic therapy (Deep PDT), the radioluminescent compound comprising a molecular conjugate made up of a radioluminescent molecule and one photosensitiser, the radioluminescent molecule being suitable for absorbing an X-ray with energy higher than an absorption threshold and for emitting luminescent radiation in the visible domain, and the photosensitiser being suitable for absorbing said luminescent radiation and producing singlet oxygen. According to the invention, the radioluminescent compound is made up of a molecule of lanthanide chlorine (LnCl3); said photosensitiser is selected among the following photosensitisers: Al(III)phthalocyanine, m-THPC, chlorin e6 (Ce6), hypericin, hypocrellin, Nile blue, oxazine 170, oxazine 1, protoporphyrin IX, 7-methoxycoumarin-4-acetic acid, bacteriochlorophyll, and auramine; and said photosensitiser is selected such as to maximise the energy transfer between an X-ray absorbed by the radioluminescent lanthanide 2 and the photosensitiser in order to produce singlet oxygen.
priorityDate 2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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