http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3060197-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0084
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10
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filingDate 2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe4570526faae11ad006743eab0197c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7010454810302ee9e8387775fdb221d1
publicationDate 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3060197-A1
titleOfInvention Delivery of agents using metastable liposomes
abstract Metastable liposomal formulations for hydrophobic drug delivery to a tissue or tissue lumen such the bladder have been developed. These are at least one micron in diameter and formed of one or more lipids having entrapped in the lipid a hydrophobic therapeutic, prophylactic or diagnostic agent. The greater stability of these liposomes, as well as the enhanced transfer of entrapped agent into the adjacent tissue, provides for better delivery, especially of hydrophobic agents such as tacrolimus which does not penetrate tissue well. The metastable liposomal formulations can be administered locally, preferably by instillation, or topically, for example, by spraying or painting, to a tissue or tissue lumen such as the bladder in need of treatment.
priorityDate 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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