http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3060098-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_970f89406471afd1d46c368c6ae6e69e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09450ee409dbdb9c799de8816d9ce55e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35343b99e24ad13e39a0408917fe539a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8aa946ef3c72f15428d5fb9fe7da8108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9f444aa9d18af0d6351e39cdebcd166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8dc16d2f690a57ad4ae3de2a26f9f75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f1aad81fde59f16b4c2c51214a8787 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1455 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-201 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1455 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-20 |
| filingDate | 2014-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_006ceffdda7d5df0d0517fe4ebee3a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad6017b4e8fa4dfc9872b2e216cff03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c0c0a6c61ad044199032b98ebc831f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9465858b095bf093386f440f8718dfd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eae734e39f43e8004e49712da816b308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a6ff428d5a34487e8314c44718e07ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b2472fb61380857ec390cc75a3ea4e |
| publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3060098-A1 |
| titleOfInvention | Improved transcutaneous organ function measurement |
| abstract | The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject. The invention further relates to a device for determining an organ function according to the method of the present invention, said device comprising a first sensor for transcutaneously measuring fluorescence of an indicator at a first position, a second sensor for transcutaneously measuring fluorescence of an indicator at a second position; and a data processing unit for fitting the values obtained by the sensors into a kinetic model of one of the preceding claims. The present invention also relates to a kit comprising a device of the present invention and an indicator compound, as well as to a computer or computer network comprising at least one processor, wherein the computer or computer network is adapted to perform the method according to the present invention. |
| priorityDate | 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.