| abstract |
The present application provides a pharmaceutical formulation comprising a folate receptor (FR)- targeting antineoplastic substance or composition, wherein the pharmaceutical formulation is configured for administration by inhalation,wherein the FR-targeting antineoplastic substance or composition is comprised in a nanoparticle and wherein the nanoparticles are comprised in microparticles,and its use in the treatment of a proliferative disease affecting at least part of the respiratory tract. The present application further provides a pharmaceutical formulation comprising an antineoplastic agent and a FR- targeting excipient, for use in the treatment of a proliferative disease affecting at least part of the respiratory tract. |