| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_123b8ea3b6d81a65f6a3e3765f7b2170 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate |
2015-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78436b4aa24495b32a6a887182d85a00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_022d90737f1b54dc9bd9023d2e8a12cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a90e22b500769a58841d971c2b77b29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df766b59c1704bda6a41cc91c1a25d0 |
| publicationDate |
2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3054017-A1 |
| titleOfInvention |
Circular RNA for the diagnosis and treatment of cardiovascular diseases |
| abstract |
The present invention associates multiple circular (circRNA) with key functions of endothelial cells. The present invention provides circRNA transcripts that are correlated with cardiovascular diseases, in particular acute myocardial infarction. The circRNA of the invention therefore serve as biomarkers in the diagnosis of cardiovascular disorders. The invention provides the new nucleic acid molecules as well as diagnostic kits and compositions comprising the nucleic acids. Modulation of the expression of the circRNA of the invention further leads to endothelial cell sprouting, and therefore is applied as a treatment for cardiovascular diseases or pathological angiogenesis. The invention provides therapeutic agents modulating circRNA expression or function. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111455037-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021074288-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112899362-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109943586-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106138081-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020257730-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106222174-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106222173-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106222174-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111455037-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018220185-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109943586-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111073981-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106138081-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106222173-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111073981-A |
| priorityDate |
2015-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |