| abstract |
The invention relates to substituted phenylalanine derivatives of formula (I), in which R1 stands for a group of formula (II) or formula (III), R2 stands for hydrogen, fluorine, chlorine, methyl, or methoxy, R3 stands for hydrogen, fluorine, chlorine, C1-C4 alkyl, methoxy, or trifluoromethyl, and R4 stands for amino, cyano, C1-C3 alkoxy, C1-C3 alkylamino, C1-C3 alkoxycarbonyl, C1-C3 alkylcarbonylamino, C1-C3 alkysulfonyl, -S(O)2NR10R11, or 5- to 7-membered heterocyclyl bonded by means of a nitrogen atom. The invention further relates to the use thereof to produce drugs for treating and/or preventing illnesses, in particular cardiovascular diseases and/or perioperative heavy blood loss. |