http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3022208-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edb72286e25757f3d54dcb5d15c9796b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 |
| filingDate | 2014-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf19ceb3018efb08918eadb66dabc0d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2583af6113aa83a9e5c49441ef239a9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47e6ecde17c91c244df9550da8f76ddd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a71118dee91fccb7431d7f3cb5e8c79 |
| publicationDate | 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3022208-A1 |
| titleOfInvention | Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives |
| abstract | The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C1-C5 alcohol. |
| priorityDate | 2013-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 334.