| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dee3727dba91e4e7aa3b26ce9efbcc21 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-66 |
| filingDate |
2014-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edcf69b5d6ddcf5a180a184a4c0a9e4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b702eaaec4e5e730ec37d76bf59812 |
| publicationDate |
2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3022183-A1 |
| titleOfInvention |
Method of racemisation of undesired enantiomers |
| abstract |
The present invention provides a very simple, efficient and economic technology for racemisation of amines, alcohols or thioalcohols where the chiral carbon (benzylic position) is located at the β-position of the heteroatom (amino, hydroxyl or mercapto group) or even more distant therefrom. Special focus is oriented in efficient and simple racemisation of an undesired enantiomer of a chiral pharmaceutically active ingredient, preferably lorcaserin or a salt thereof, preferably the hydrochloride salt thereof. The approach according to the invention enables a use of cheaper and shorter racemic synthetic schemes not requiring expensive and toxic reagents and catalysts. Present methodology enables industrialy convenient process. |
| priorityDate |
2013-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |