| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66e061087b8b0ca4bda35df8e395be73 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90731be09786bccf219c667ec1b3518e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623e752018bf9a53fbe49833f7e593ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d4ab8a9f9dc1d95f70c745e0e3949e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027dad87f7fa296fae0f4df85e6bf856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6319a556a6409287ed6301e8c8d6f024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a470080a1971b05f778073a839fe251a |
| publicationDate |
2016-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3006457-A1 |
| titleOfInvention |
Mutated pseudomonas exotoxins with reduced antigenicity |
| abstract |
The invention provides mutated Pseudomonas exotoxins (PE) that have reduced immunogenicity compared to PEs containing the native sequence. The PEs of the invention have one or more individual mutations of positions of the native sequence of PE that reduce antibody binding to one or more PE epitopes. Nucleic acids encoding the mutated PEs, chimeric molecules comprising them, compositions comprising the chimeric molecules and methods of using them, are also provided. |
| priorityDate |
2005-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |