Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce384cea17765179fd01cd5c80f294ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_340feb1a36c104f8b4978a8261ff3517 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D255-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D255-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
filingDate |
2014-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6d78dd6833673c29d16f643218c76f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbfadd08a232c03d4df316b1f716256f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef02af3a418c01565f44c181c232cfbf |
publicationDate |
2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2991969-A1 |
titleOfInvention |
Metal complexes and fluorination thereof |
abstract |
The present invention relates to a method of labelling biological molecules with 18F, via attachment of fluorine to a metal complex, where the metal complex is conjugated to the biological molecule. The invention highlights the incorporation of hydrogen bonding (H-bonding) into the metal complex scaffold, and how this can be utilised to improve the kinetics of fluoride incorporation. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11103604-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11135322-B2 |
priorityDate |
2013-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |