Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01047 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate |
2014-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2ce1e420ba30c5378b38a71d518a4f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f5224e47651afabbbca60883024e4e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9c3f68e8e1d1c610674a6bcfab739f6 |
publicationDate |
2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2986724-A1 |
titleOfInvention |
Designer cells for enantioselective reduction of ketones and use thereof in efficient production of enantioenriched alcohols |
abstract |
The present invention is to provide a preparation of variant recombinant whole cell biocatalysts, referred herein as "designer cells" having significantly enhanced carbonyl reductase activity for use in the efficient production of variant industrially important enantiomerically enriched alcohols. More specifically, the alcohol is optically pure ethyl (S)-4-chloro-3-hydroxybutyrate, which is useful as chiral building block and an intermediate for the production of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors. |
priorityDate |
2013-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |