| abstract |
The invention provides compounds with the structure of Formula I: wherein R6-R10, R6'-R9', R20 and R21 are as defined in the claims, useful in methods of treating neurodegenerative diseases or disorders associated with compromised axonal function. The present disclosure provides compounds, compositions and methods of synthesizing compounds that are effective against neurodegenerative disorders, including their action as neurotrophic and axonotrophic agents. The present disclosure provides methods for the therapeutic treatment of neurodegenerative disorders, and methods of prophylaxis against neurodegenerative disorders. |