| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 |
| filingDate |
2014-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4463fc75af0257291c0e4443bb8b7ddd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e418a81137b3e4b9c72601884061bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a997fc50a8f2cd1ad80e9b57d23a544a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f251ca17fc87c8a31b0f1579380feb41 |
| publicationDate |
2016-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2964647-A1 |
| titleOfInvention |
Inhibitors of bruton's tyrosine kinase |
| abstract |
This application discloses compounds according to generic Formula (I) wherein all variables are defined as described herein, which inhibit BTK. The compounds disclosed herein are useful to modulate the activity of BTK and treat diseases associated with excessive BTK activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formula (I) and at least one carrier, diluent or excipient. |
| priorityDate |
2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |