| abstract |
Methods, systems and compositions are provided for analyzing one or more nucleic acid molecules. The methods, systems and compositions may comprise one or more target specific-oligonucleotide probes (TSPs). The TSPs may hybridize to nucleic acid molecules that are less than or equal to 200 nucleotides in length. The nucleic acid molecules may be small RNA molecules (e.g., miRNA, ncRNA, siRNA, shRNA). The methods, systems and compositions find use in a number of applications, for example, isolation of nucleic acid molecules, analysis of low abundance nucleic acid molecules, and/or enrichment of nucleic acid molecules. |