http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2961416-A1

Outgoing Links

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filingDate 2013-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b00d81c176d2d9af73a6cbfd460ccf69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0482edd79db39c2231623ac33613310b
publicationDate 2016-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2961416-A1
titleOfInvention Methods of producing enriched populations of tumor reactive t cells from peripheral blood
abstract Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of peripheral blood mononuclear cells (PBMCs) from a sample of peripheral blood; (b) specifically selecting CD8+T cells that also express PD-1 and/or TIM-3 from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed.
priorityDate 2013-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 22.