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filingDate 2014-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2956557-A1
titleOfInvention Compositions and methods of use thereof for identifying anti-viral agents
abstract The present disclosure provides a recombinant expression vector comprising a nucleotide sequence encoding a herpesvirus transactivator, where the nucleotide sequence is operably linked to a herpesvirus control element. The present disclosure provides cell lines genetically modified to express a herpesvirus transactivator under the control of a herpesvirus control element. The present disclosure provides methods of identifying agents that disrupt feedback regulation of a herpesvirus transcriptional control element by a herpesvirus transactivator.
priorityDate 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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