| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-904
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-03004 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54 |
| filingDate |
2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36be9e8b48bac3d0cff6ce89bfa23b3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_525df262892661709ef09f952a6727ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b499eaa67e8d35ccabaa8294eda0267
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a6f7392022b07d9df491f695d63e1fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4645840a43ee9bc6037582fe80280cfd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cc5a0c422a09b374c7d07aff21fb87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47d494112eb81ca139b4abd8a9cd1878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d757a4742a0d2255db2f00c6f98c40c7 |
| publicationDate |
2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2948547-A1 |
| titleOfInvention |
Novel glucose oxidases derived from aspergillus niger |
| abstract |
Disclosed herein are novel glucose oxidase variants having besides the two substitutions T30V and I94V according to SEQ ID NO: 1, additionally at least one further amino acid substitution in the polypeptide sequence in any of the positions S53; A137; A173; A332; F414; and V560. The thus optimized glucose oxidase variants exhibit specificity for glucose and significantly reduced oxygen-consumption rates. In another aspect, the present invention provides for glucose oxidase variants having significantly reduced oxygen-consumption rates and/or increased enzyme activity for electron mediators other than oxygen. The invention also provides for an assay device bearing at least one of the herein disclosed GOx variants for improved blood glucose measurements. |
| priorityDate |
2013-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |