http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2940030-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10
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filingDate 2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ee8244820b207bbb48c4688959585f6
publicationDate 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2940030-A1
titleOfInvention Method for producing p1,p4-di(uridine 5'-)tetraphosphate
abstract A method for producing P 1 ,P 4 -di(uridine 5'-)tetraphosphate (UP 4 U) that can avoid reduction of the synthetic efficiency without using UTP free is developed. n A method for producing UP 4 U comprising reacting a phosphoric acid-activating compound represented by formula [II] or [III] with a phosphoric acid compound selected from the group consisting of UMP, UDP, UTP and a pyrophosphoric acid or a salt thereof (excluding UTP free) in water or a hydrophilic organic solvent, in the presence of a metal ion selected from the group consisting of an iron (II) ion, an iron (III) ion, a trivalent aluminum ion, a trivalent lanthanum ion, and a trivalent cerium ion. nwhere, in the formula [II], R 1 represents a uridyl group binding to the 5'-position, X represents a heterocyclic group, and n represents an integer of 1 or 2, where, in the formula [III], X represents a heterocyclic group selected from the group consisting of an imidazolyl group, a benzimidazolyl group, and a 1,2,4-triazolyl group.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3546472-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190067162-A
priorityDate 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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