| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 |
| filingDate |
2013-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f684058ea19eadada95e6af3bbb6197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d764ce01aa1cd133c633d559238ea29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de1de6c3b694319d0c868076cee5ede8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb1916e9a5068fb24f47d77f0bae7e49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab0b6f5f2b78c7413d6f693e22c3827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed1164aee1967603b36723abe76cf16 |
| publicationDate |
2015-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2928473-A1 |
| titleOfInvention |
Regioselective n-2 arylation of indazoles |
| abstract |
A novel process is provided for the efficient preparation of an asymmetric compound of structural formula I: comprising a copper-catalyzed, carbon-nitrogen cross-coupling step. The process described as part of the present invention can be used to manufacture poly (ADP-ribose) polymerase (PARP) inhibitors, which may be useful for the treatment of cancer. In particular, the present invention describes a process for the manufacture of the PARP inhibitor, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629137-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11161834-B2 |
| priorityDate |
2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |