abstract |
The invention discloses a method of treating cancer refractory to an anticancer agent comprising administering to a cancer patient a pharmaceutical composition comprising at least one compound of Formula (1) Where R 1 is selected from the group consisting of -NH 2 , -NH-CH 2 -COOH, -NH- CH(CH 3 )-COOH, -NH-C(CH 3 ) 2 -COOH, -NH-CH 2 -CH 2 -OH and -N-(CH 2 CH 2 OH) 2 or a pharmaceutically acceptable salt of such a compound, and an anticancer agent. |