http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2921496-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eaac602c226f8ec1760187c3d8028673 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 2015-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ab209fefc73346793578c4f0dad4119 |
| publicationDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2921496-A1 |
| titleOfInvention | Method for synthesizing a psoralen derivative |
| abstract | The invention relates to a process for the synthesis of a compound of formula (I) for which R1 is chosen from the group consisting of a hydrogen atom and a linear or branched C1-C6 alkyl group and R2 is chosen from the group consisting of a hydrogen atom, a linear or branched C1-C6 alkyl group, and a linear or branched C1-C6 alkoxy group, said process comprising the following successive steps: (a) acetylation of a compound of formula (II) for which R1 and R2 are defined as above, to yield a compound of formula (III) for which R1 and R2 are defined as above, (b) subjecting the compound of formula (III) obtained in the preceding step (a) to a Fries rearrangement to yield a compound (IV) for which R1 and R2 are defined as above; and (c) cyclization, reduction and aromatization of the compound of formula (IV) obtained in the preceding step (b) to lead to the formation of the compound of formula (I). |
| priorityDate | 2014-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.