| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2013-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1953285b1dbddc78d14f945d931bf7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b61ab449254d3ee925815094dd58974e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c20717644ed4365534c77005f31a944c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed988ec54533c427f248aee43dba308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e20f28a1551f3125ae9f8a7fc7a5f89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e604238fc0c600dc01fac7ab3dae633
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7606ef325f68ee7f9fe1c64b917ce30c |
| publicationDate |
2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2919770-A2 |
| titleOfInvention |
Inhibition of hif-2 heterodimerization with hif1 (arnt) |
| abstract |
Provided is a method of inhibiting heterodimerization of HIF-2α to HIF1β (ARNT) comprising binding certain small molecules to the HIF-2α PAS-B domain cavity but not to HIF1α and inhibiting HIF-2α heterodimerization to HIF1β (ARNT) but not inhibiting HIF1α heterodimerization to HIF1β (ARNT). Those certain small molecules are also referenced synonymously as HIF2-HDI and HIF2α heterodimerization inhibitors and also simply as certain small molecules. |
| priorityDate |
2012-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |