| abstract |
The invention provides Neuregulin or a functional fragment thereof for use in a method of preventing, treating or delaying heart failure or preventing cardiac hypertrophy in a mammal, wherein the method comprises releasing Neuregulin to the mammal over a period of 4 hours or longer per day by extended release means such as an osmotic pump, a syringe pump, packaging into a liposome or microsphere or coupling to a polymer. |