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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c99f776f7f30bd86951e3096b70937
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publicationDate 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2914282-A1
titleOfInvention Recombinant clostridium botulinum neurotoxins
abstract The invention provides a nucleic acid sequence comprising a sequence of contiguous nucleotides, wherein said sequence of contiguous nucleotides has at least 90% sequence identity to the nucleic acid sequence of SEQ ID NO: 1,and wherein said sequence of contiguous nucleotides encodes a single-chain BoNT/E1 protein. The present invention also provides methodsfor producing soluble single-chain BoNT/E protein in an E. colihost cell, together with methodsfor producing soluble di-chain 10 BoNT/E1 protein.
priorityDate 2012-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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