| abstract |
The present invention provides libraries of polypeptides, polynucleotides, or host cells, wherein said library includes at least one polypeptide variant of the Parvibaculum lavamentivorans short-chain alcohol dehydrogenase, or a polynucleotide comprising a nucleotide sequence encoding said variant, and/or a host cell including said polypeptide variant or the polynucleotide comprising the nucleotide sequence encoding said variant. Also disclosed are variants of the Parvibaculum lavamentivorans short- chain alcohol dehydrogenase, polynucleotides comprising a nucleotide sequence encoding said variants, and host cells including said variant or said polynucleotide. Also provided is a method for stereoselective reduction ketones. |