| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-599
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2312
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2304
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-2306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-231 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781 |
| filingDate |
2013-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d2a1cecde809aaf8570d662d7cd9e90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8603ff381167378c2311f5b8fb346de3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53bb916a5c84aced98789d3a4a02d9ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e79b6b4c2ed06473eaa919b4db16f7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea3d6b4c5477d32c32c7914f62d7db90 |
| publicationDate |
2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2893002-A1 |
| titleOfInvention |
Methods of expanding and assessing b cells and using expanded b cells to treat disease |
| abstract |
Provided herein are methods of expanding B cells, and particularly B 10 cells capable of producing IL-10, ex vivo. The methods include incubation of harvested B cells in the presence of lL-21. The B cells may be further expanded by culturing with IL-4 and feeder cells expressing CD154 and BLyS (BAFF) prior to contacting the cells with IL-21 and the feeder cells. Compositions comprising the ex vivo expanded B cells and methods of using the expanded B cell-containmg compositions to treat diseases or conditions are also provided. Methods of assessing B10 cell function in a subject are also provided. |
| priorityDate |
2012-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |