| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0b73680469ccaf3eb4222e67c700665 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-173 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173 |
| filingDate |
2010-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c6cdfc257b06a8a2a4b86b2c5c70236
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c20edec4cf7040f8a2b66ead312b865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_777937246205b305b121926aba255b2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b24a73d184dd9376720baf011989eb2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51844169bcdeba4c79469a8287df3261 |
| publicationDate |
2015-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2891660-A1 |
| titleOfInvention |
Process for the preparation of cladribine |
| abstract |
A method of making cladribine with an increased purity is provided by na) dissolving crude cladribine in a protic solvent in the presence of a base to form a solution comprising dissolved crude cladribine; nb) maintaining the solution at an elevated temperature so that the solution is homogeneous until the amount of protected or partially protected nucleoside impurities in the solution is reduced to a pre-determined upper limit; nc) cooling the solution of step b) so that crystals of cladribine are formed and isolated. |
| priorityDate |
2009-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |