Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0444efde206a2f829562761e58b7e1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bceffddb90b9b3da8a772212961764b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate |
2013-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e26e28ca168d8c50adb02742c34121b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35fde7e3d88b33af202f485f3109cab9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec5e3712d1473ece3f4024364b346b67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3d20e01df3363de3042b57cfe69e70a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b05d1582444d95ed70bc41d83b2a11aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_484fd7ec897bcf8b711680f7e0a7b86b |
publicationDate |
2015-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2881403-A1 |
titleOfInvention |
Scavenger containing protein formed from tandem-type multimer of mutant extracellular domain of protein g |
abstract |
The purpose of the present invention is to provide a superior protein with more decreased binding property to the Fc region of immunoglobulin and/or more decreased binding property to the Fab region thereof in the weakly acidic region in comparison with a protein containing an extracellular domain of a wild-type protein G without spoiling the high antibody binding property in the neutral region, and to allow the antibody to be easily captured and recovered without denaturing it by means of a capturing agent and column comprising the above protein. n The present invention relates to a capturing agent for an antibody, immunoglobulin G or a protein comprising an Fc region of the immunoglobulin G, wherein a protein consisting of a tandem-type multimer of extracellular domain mutants that have binding property to the protein comprising the Fc region of the immunoglobulin G is immobilized to a water-insoluble solid support via mainly an amino group, and a column for a chromatography for separating and purifying the protein, which is filled with the capturing agent. |
priorityDate |
2012-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |