| abstract |
The invention relates to biomarkers for diagnosingand/or monitoring tuberculosisin both immunocompetent and immunocompromised individuals, monitoring the responses of individuals to anti-mycobacterial chemotherapy, monitoring the progression of latent tuberculosis to active tuberculosis, differentiatingactive tuberculosis from latent tuberculosis, and from other clinical conditions that mimic tuberculosis (TB).The invention also relates to methods fordiagnosing, treatingand monitoring tuberculosis using said biomarkers.The above pertain in all aspects both to pulmonary and extrapulmonary Mycobacterium.tuberculosisinfections, with Mycobacterium. tuberculosisbeing the causative organism in tuberculosis. |