Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18471 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32322 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-015 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
2013-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e34c662b37309c33e2323553fe01f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd38302d9cd14ba19d86497ab41a700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e0938eec1d2e09bd6b45e701f4ede5a |
publicationDate |
2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2873728-A1 |
titleOfInvention |
A subunit vaccine platform based on multimeric ribonucleoproteins comprising nucleoproteins of a non-segmented negative-strand RNA virus as carriers of heterologous polypeptides |
abstract |
The present invention relates to a subunit vaccine platform based on multimeric ribonucleoproteins (RNPs) comprising nucleoproteins of a non-segmented negative-strand ribonucleic acid (RNA) virus as carriers of heterologous polypeptides. The present invention also relates to multimeric RNPs resulting from the assembly of at least 200 fusion proteins with a cellular RNA, or to recombinant yeasts or yeast lysates expressing these multimeric RNPs. It also concerns a process for the preparation of these multimeric RNPs or recombinant yeasts or yeast lysates. In particular, the present invention relates to their use as active ingredient for the in vitro production of an immunogenic composition or in eliciting a protective prophylactic or a therapeutic immune response against said heterologous polypeptide in a host in need thereof. Recombinant yeasts or yeast lysates of the invention can also be used as expression and vector systems for delivery to a host. |
priorityDate |
2013-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |