http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2865686-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ff3005508304394801e265e503b811 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2013-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24af4ec3ec881e5cbee91d4ef14e8561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dfd891615b9f260dd62b97f90e943b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6092354a46e19dbe390e72eeef65268c |
publicationDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2865686-A1 |
titleOfInvention | Egfr-binding peptide |
abstract | Provided are a substance capable of binding to EGFR specifically with a high affinity and a pharmaceutical agent containing the substance. n Apeptide which contains at least an amino acid sequence represented by the formula (1), (2) or (3) and is composed of 12 to 50 amino acids: n n X 1 -His-X 2 -X 3 -Asp-X 4 -X 5 -X 6 -X 7 -X 8 -Trp-His (1) n n(In formula (1), X 1 represents Trp or Phe; X 2 represents Leu, Met, Ile or Val; X 3 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys; X 4 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys; X 5 represents Trp, Phe or Tyr; X 6 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg; X 7 represents Asn, Gln, Asp, Glu, Ser, Thr, Ala, Gly, Lys or Arg; and X 8 represents Ala, Gly, Ser, Thr, Asn, Val or Cys); n n Phe-His-Asp-Trp-X 11 -Pro-X 12 -X 13 -X 14 -X 15 -X 16 -X 17 (2) n n(In formula (2), X 11 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys; X 12 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His; X 3 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn; X 14 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys; X 5 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe; X 16 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe; and X 17 represents Asp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, Arg or His); and n n Leu-His-X 21 -Ser-X 22 -Trp-Met-X 23 -X 24 -X 25 -X 26 -X 27 (3) n n(In formula (3), X 21 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg; X 22 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His; X 23 represents Tyr, Phe, Trp, His, Leu, Met, Ile, Val, Cys or Ala; X 24 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn; X 25 representsAsp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, ArgorHis; X 26 represents Ile, Val, Leu, Met, Ala, Phe, Tyr, Trp or Gly; and X 27 represents His, Tyr, Phe, Lys, Arg, Leu, Met or Ala.) |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018061004-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11739163-B2 |
priorityDate | 2012-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.