abstract |
The present invention deals with a method for the preparation of 2,4- dihydroxybutyric acid (2,4-DHB) comprising the successive steps of converting malate, succinyl-CoA and/or glyoxylate into malyl-CoA, converting malyl-CoA previously obtained into malate-4-semialdehyde, and converting malate-4- semialdehyde into 2,4-DHB using a DHB dehydrogenase. |