http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2841462-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a21dc8f18ecbf2bc1565a49532dc9f7b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-298 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 |
filingDate | 2013-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb849cc528abf76a01766fc2eb0106ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bf36520efe3d9417a4a00bedf609954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ea2d3b20cba8eaf97dc6429b0e4a131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed8009e9ea385ccda70b8fa10b3750b2 |
publicationDate | 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2841462-A1 |
titleOfInvention | Crosslinked hyaluronan derivative, method of preparation thereof, hydrogel and microfibers based thereon |
abstract | The invention relates to a crosslinked hyaluronan derivative in the form of a hydrogel or microfibers, and to a method of preparation thereof, consisting in a C-C coupling reaction. The C-C coupling reaction is performed via reaction of a hyaluronan derivative carrying a terminal aryl-halide and/or aryl-borate group, and a hyaluronan derivative carrying an alkenyl or alkynyl group, in water, phosphates buffer or a mixture of an organic acid and an alcohol, and in the presence of a palladium active catalyst. The palladium active catalyst may be e.g. a complex of palladium (II) acetate and an inorganic or organic base, or a complex of palladium (II) and 2-amino-4,6-dihydroxypyrimidine. |
priorityDate | 2012-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.