abstract |
The present invention relates to methods of diagnosing cancer, determining the prognosis of a patient diagnosed with cancer and identifying a compound for treatment of cancer, using MED15 and/or MED12 as markers. In particular, the cancer is prostate cancer, castration-resistant prostate cancer (CRPC), distant metastatic CRPC or local recurrent CRPC. Furthermore, the invention relates to compounds for the treatment of cancer and use of MED15 and/or MED12 for diagnosis of cancer or prognosis of a patient suffering from cancer. |