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filingDate 2013-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_193cfe2d3b0e22924cb0ad714cc27f9f
publicationDate 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2816344-A1
titleOfInvention Optical analysis device using single particle detection technique, optical analysis method and computer program for optical analysis
abstract In the scanning molecule counting method using the light measurement with a confocal microscope or a multiphoton microscope, there is provided a technique enabling improvements in its sensitivity and/or S/N ratio. In the optical analysis technique of detecting an existence of a single particle in a sample solution according to the present invention, the position of a light detection region is moved in the sample solution; the light intensity from the light detection region is measured so that light intensity data will be generated; a first occurrence probability in assuming a first condition that no single particles exist in the light detection region and a second occurrence probability in assuming a second condition that a single particle exists in the light detection region for a time variation of light intensity value on the light intensity data are computed; and a signal indicating each single particle is detected by detecting the time in which the single particle existed in the light detection region based on those occurrence probabilities.
priorityDate 2012-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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