Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68470742c37db68ce35b8ae425ce50cc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
filingDate |
2012-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_504c716600f16ed12f69500cba50f1fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f597dedafcc5092610018f5a08039789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d77eb17a4fe4475432594d794acd82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab91826ad2776ca667e9b123b0d8be1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21c94812fa199b1817b99c7853420b62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_516c66e1a084fe28f9334f31974f7f9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_754cae4f28cd84a48de9561bbe80287d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52ed2cb3ec32a57912e9b9fde3e45ebc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_676c26ba2791bf644d9efd4540be883c |
publicationDate |
2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2809680-A1 |
titleOfInvention |
Gpcr with improved cell surface expression |
abstract |
The present invention surprisingly shows that the addition of a heterologous viral-GPCR (G protein-coupled receptor) derived sequence at the amino terminal end of GPCRs improves cell surface expression of such receptors in eukaryotic cells. Transfected cells expressing the above heterologous viral GPCRs on their surface are useful for cell based assays to identify test compounds that increases or modulate activity of a GPCR or a ligand of a GPCR for example for drug discovery, development of novel flavors in the food industry or development of sensors based on odor GPCRs. In addition, membrane extracts derived from transfected cells may be used for example for assays of compounds in drug discovery or for development of sensors comprising such membrane extracts for identification and/or quantification of volatile organic compounds. |
priorityDate |
2012-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |