| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1aa877e508ad0f3a2ed38b5c6157f444 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bd15c9ebe33fd36ce00b088ff35d339
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55e0bff2bebb009151a13d14db02ae1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f5137292e6ebdd120e20ff4c17fe79 |
| publicationDate |
2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-2799451-A1 |
| titleOfInvention |
Generation and profiling of fully human HuCAL GOLD®-derived therapeutic antibodies specific for human CD38 |
| abstract |
The invention pertains to a human or humanized anti-CD38 antibody or functional fragment thereof for use in a method of treating a tumor disease, in particular a haematological disease, by inducing specific killing of tumor cells that express CD38 by CD38 cross-linking. The antibody for use according to the invention include an antibody characterized by a variable heavy chain having the amino acid sequence of SEQ ID NO:6 and a variable light chain having the amino acid sequence of SEQ ID NO:14, an antibody characterized a variable heavy chain having the amino acid sequence of SEQ ID NO:5 and a variable light chain having the amino acid sequence of SEQ ID NO:13 as well as variants thereof. |
| priorityDate |
2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |