Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5073a0063d6be9e25c14d2af0a1ee89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e76dda3227564442b9a3e348d2586e63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35fb8e6f1ca58625d0ab18bf62997320 |
publicationDate |
2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2793026-A1 |
titleOfInvention |
New method for monitoring cancer and/or inflammatory reaction based on relb phosphorylation |
abstract |
The present Inventors demonstrated that the RelB subunit of NFκB plays a crucial role in promoting cell migration. More precisely, they identified that this pro-migratory activity is mediated by the activation of the NFκB pathway through ReIB phosphorylation at serine 472. In a first aspect, the present invention proposes to monitor the activation of the NFκB pathway by following the phosphorylation status of said serine. Also, the present invention discloses methods and kits for prognosing the evolution of a disease involving cell migration in a subject - treated or not - suffering thereof, based on the detection of said ReIB-5472 phosphorylation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299726-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108124451-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018524016-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022106539-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7099951-B2 |
priorityDate |
2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |