http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2792754-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ed9a8826e874e45a3047da75b569965 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2013-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8ffebe45ee430bb0f9a2f73cf47c5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed7af94a1f6b13cc8f50fcb2ea2861aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b8c82a9152a66ea308428d560bf4286 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5bd6acddf1647110ee56ae9420e97bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30e21f697086685cda256c0531a947f3 |
| publicationDate | 2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2792754-A1 |
| titleOfInvention | Biomarkers for epilepsy |
| abstract | The present invention relates to a group of epilepsy biomarkers comprising (i) SNP rs2740574; (ii) SNP rs1799735; (iii) SNP rs1695; (iv) SNP rs6280; and the locus of the human glutathione S-transferase theta-1 (GSTT1) gene. The invention particularly relates to this group of biomarkers as marker for protection against drug-resistant epilepsy. The group of biomarkers may additionally comprise at least one clinical marker selected from the group comprising (i) a focal seizure with secondary generalization; (ii) age at confirmed diagnosis of epilepsy; (iii) atrophy of hippocampus or medial temporal sclerosis; and (iv) the presence of a brain tumor. The present invention further relates to a method for detecting protection against drug-resistant epilepsy in a subject, a method for monitoring epilepsy therapy, a method of identifying an individual as eligible for an aggressive epilepsy therapy, a composition for detecting protection against drug-resistant epilepsy in a subject, a corresponding kit and a microarray for the analysis of protection against drug-resistant epilepsy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109295189-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106995936-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200145930-A |
| priorityDate | 2013-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 483.