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publicationDate 2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2791677-A1
titleOfInvention General strategy for antibody library screening
abstract A generally applicable method for the selective covalent attachment of a reporter molecule to a replicating entity that allows one to obtain specific binders from a single round of library screening is disclosed. For example, selective biotinylation of phage particles and yeast cells displaying a binder to any given target can be achieved via application of a coupled enzyme reaction that includes a peroxidase, an oxidase and a catalase.
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